SLAS2021 Special Interest Groups

One of the key benefits of attending an SLAS conference is the ability to meet with others in your area of interest and expertise through the SLAS Special Interest Group (SIG) Program. One of the benefits of SLAS2021 Digital is that these unique and focused presentations are available for you to view on-demand! 

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Compound Combination Screening Special Interest Group
Open to view video.
Open to view video. In our SLAS SIG, we want to assess the current state of combination screening in the field, guiding the audience through a discussion on proven experimental designs and quality control, preferred assay technologies, and how to reliably identify synergic or antagonistic behavior of your compound combinations.
You must register to access.
Absorption, Distribution, Metabolism and Toxicology (ADMET) Special Interest Group
Open to view video.
Open to view video. Opportunities for Integrating in vitro Transporter Tools into Preclinical Discovery Programs to Predict Clinical Outcomes Description: Many cell-based transporter assays are available to guide compound optimization in preclinical discovery and development. They offer many advantages including lower cost, faster turn-around-time, and higher reproducibility than in vivo studies in preclinical species. However, they also offer many challenges in how to interpret when generated in the myriad of in vitro assays and whether they may be predictable for drug-drug interactions (DDI) in IND filings. This presentation will provide some mechanistic transporter tools that may support preclinical drug discovery from single to multiple transporter models to 3D-like HEPATOPAC model and a case study to predict clinical DDI with folate transport.
You must register to access.
Academic Drug Discovery Special Interest Group
Open to view video.
Open to view video. The mission of the Academic Drug Discovery SIG is to enable greater interaction between academia, pharmaceutical research companies, suppliers and other technical companies. Through a range of unique programs and events, the Academic Drug Discovery SIG will build bridges between the academic and applied sciences. These ties will result in better skilled candidates for industry as well as enhanced support for academic centers with programs focused on drug discovery, screening, automation and related disciplines.
You must register to access.
Sample Management Special Interest Group
Open to view video.
Open to view video. Sample Management in the Time of COVID-19 The year 2020 was a year of unprecedented challenges around the world due to the COVID-19 pandemic. During this session, we will invite SIG members to share how the challenges of COVID-19 affected their Sample Management operations in 2020 and discuss lessons learned. We will also hear an update from Lynn Rasmussen, former head of the Labware Leachables SIG, which merged with the Sample Management SIG in 2020.
You must register to access.
HCS/HCA Data and Informatics Special Interest Group
Open to view video.
Open to view video. High content imaging approaches to organs-on-chips: recent advancements and future prospects Organs-on-chips are miniaturized 3D microfluidic devices that reconstruct the multicellular and physical microenvironment of specific tissues or organs and can be used to model normal or disease level functions. In this SIG, we will discuss: (1) how organs-on-chips recapitulate physiological conditions and offer an alternative or parallel preclinical model to study biological mechanisms or assess drug efficacy/toxicity; (2) high-content imaging assays that are being applied to organs-on-chips; and (3) current opportunities, challenges and development areas for the future of HCS/HCA applications using organs-on-chips platforms.
You must register to access.
Screen Design and Assay Technology Special Interest Group
Open to view video.
Open to view video. Phenotypic high content screening and affinity screening of DNA-encoded libraries: approaching disease targets from different directions The SIG will meet to hear short presentations highlighting opportunities and challenges presented by two very different drug discovery approaches: phenotypic high content screening and affinity screening of DNA-encoded libraries. Following the two short talks by experts in their respective fields, the floor will be opened for questions and what we hope will be lively discussion. We encourage attendance from all levels in pharma, biotech, technology vendors, non-profits, and academia.
You must register to access.
Stem Cells and 3D Microtissues Special Interest Group
Open to view video.
Open to view video. Engineering Human Organoids and Complex Tissues
You must register to access.
Technology Transfer and CRO/CMO Project Management Special Interest Group
Open to view video.
Open to view video. About the Technology Transfer and CRO/CMO Project Management Special Interest Group: As biopharmaceutical companies seek to increase capacity, free up resources, accelerate clinical timelines, and meet business continuity requirements, technology transfer to contract research organizations (CRO) or contract manufacturing organizations (CMO) has increased dramatically. This special interest group (SIG) will provide a platform for industry colleagues to address and discuss the challenges and key factors considered to be important for achieving successful transfer and facilitate interactions with multiple stakeholders.
You must register to access.
WomXn of SLAS Special Interest Group
Open to view video.
Open to view video. Join the WomXn of SLAS on January 26th at 1pm EST for a 1-hour panel discussion entitled “I wish I had known”. Meet 4 women across academia, pharma/biopharma and the vendor-side of industry and hear them share their stories about career advice they wish they had known early on. Topic examples of what we will discuss include: “how can you tell the difference between being overworked and challenged” and “have you focused more on what you’re good at, or did you explore different areas”. We will reserve time for questions from the audience as well! Panelists: • Mariafrancesca Scalise, University of Calabria • Robyn Rourick, Genentech • Cathy Tralau-Stewart (UCSF to Takeda) • Debbie Bowers, BioDot and BioSoft Integrators Moderated by: Michelle Arkin, UCSF
You must register to access.
Molecular Biology and Protein Science Standards Special Interest Group
Open to view video.
Open to view video. The long-term objective of the Molecular Biology and Protein Science Standards SIG is to have these standards adopted across academia and industry to provide the basis for an open database. This database will serve two major purposes: (1) improve our ability to successfully generate proteins of interest and (2) provide foundational data to explore the feasibility of building machine learning models for soluble, functional protein design.
You must register to access.
Phenotypic Drug Discovery Special Interest Group
Open to view video.
Open to view video. The phenotypic drug discovery (PDD) SIG will serve as a discussion forum for the global research community to share/discuss/debate topics related to PDD research. Participants will share their experiences, perceptions, and thoughts on the advantages/disadvantages of PDD and whether/how PDD complements targeted drug discovery (TDD) strategies. Related topics such as target identification/validation, chemical diversity, chemical genomics, chemo-informatics, poly-pharmacology, translational pharmacology, biological model systems and patient tailoring are also in scope.
You must register to access.
3D Printing and Additive Manufacturing Special Interest Group
Open to view video.
Open to view video. This SLAS SIG is open to all experience levels, from those interested in the idea to people who print things every day. If you have ever wanted to take an idea and turn it into a real thing that you can use in the lab, then this group is for you. This community provides collaboration and resources for people thinking about getting into 3D printing and additive manufacturing, and those who already are printing on a daily basis. Share how you use 3D printing in your laboratory areas and discover how 3D printing enables highly custom and rapid prototyping.
You must register to access.